Husos Architects’ work advances in an ongoing dialogue between design and research. Founded in 2003 between Spain and Colombia, the architecture and urban planning office stands out for addressing different scales, from the micro to the global, responding to the requirements of specific users but weaving deep contextual networks with the environment and beyond. How do they effectively approach this complexity, in turn promoting social transformation? We spoke with Diego Barajas and Camilo García Barona about their processes of approaching users and other agents involved –not only humans–, about how they address the colonization of the biosphere that has caused climate change, and about their inquiry into activism from a series of battlefields habitually neglected in traditional discourses of architecture.